Khan Yunis is one of the largest cities in the Gaza Strip, second in size only to Gaza City. It is the largest urban center in southern Gaza.
It has been the location of fierce fighting between the IDF and Hamas amid Operation Swords of Iron, the ongoing war between Israel and Hamas, at the time of writing.
The IDF struck Khan Yunis hospitals twice on Tuesday prior to the sirens.
In April, the IDF claimed to have killed Eslaih, a member of Hamas's Khan Yunis Brigade, in a Khan Yunis strike.
A documentary about healthcare workers in Gaza amid the warzone has been put on an indefinite delay due to a Hamas-linked documentary that is now under review.
On Friday, the military finished establishing the Morag Corridor, which separates Rafah and Khan Yunis.
The demand evacuations from Khan Yunis neighborhoods was announced by IDF's Arabic-language spokesperson, Col. Avichay Adraee.
Hassan Eslaih was known for his now-famous photo where former Hamas leader Yahya Sinwar is seen giving him a kiss on the cheek.
A Hamas command and control center that was used for planning and executing terror attacks was destroyed during the activity, the IDF said.
In the early afternoon, the IDF fired artillery at Shejaia, east of Gaza City, during its operations in the area.
Matan Zangauker is not listed to be released in the first phase of the ceasefire-hostage deal.
Among the banners printed in English, Hebrew and Arabic is the phrase “no migration except to Jerusalem” - a likely reference to Trump’s relocation plans.