Iran, Hezbollah, and Hamas have targeted the Dimona reactor in the past and are likely to do so in the future.
"The Iranians are accumulating [uranium]. They say it's for civilian purposes, but we haven't seen much of that in use. It is, in fact, being stored."
As IAEA reports show Iran's nuclear efforts advancing, the US and its allies have few viable options to respond.
Asked in a radio interview about a hypothetical nuclear option, Heritage Minister Amichai Eliyahu had replied: "That's one way."
President of the Atomic Energy Organization of Iran also critiqued Western countries in meeting with Director General of the IAEA in Vienna.
Ukraine and Russia accuse each other of shelling around the station and the IAEA has been trying to set up a safety mechanism to prevent accidents.
DIPLOMATIC AFFAIRS: The presidents and the ambassador may have wanted to shift focus away from defense, but it plays a huge role in ties between the countries.
Oppenheimer and his team of scientists tested the weapon there before it was eventually dropped on the Japanese cities Hiroshima and Nagasaki
The IAEA and Iran said they had agreed to make progress on various issues, including a long-stalled IAEA inquiry into uranium particles found at three undeclared sites in Iran.
Grossi's statements came after extended meetings with key officials in Iran over the weekend.
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